Flights from Madrid (MAD) to Istanbul (IST)

Flight schedules from Madrid to Istanbul with Star Alliance member carriers

Please note that the flight schedules of our member carriers are subject to change on short notice. We recommend using our member airlines information page. for the latest flight updates, details on booking flexibility, as well as specific Frequent Flyer Program information.

Outbound (25)

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Madrid ES
MAD12:00
4h 15m
No stops
Istanbul TR
IST17:15
Madrid - Istanbul
Turkish Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Turkish Airlines TK 1858
  Madrid. ES
  MAD 12:00
  4h 15m
  1688 Miles
  Istanbul. TR
  IST 17:15
  Airbus A330-300 Passenger
  Operated by Turkish Airlines
Madrid ES
MAD14:30
4h 25m
No stops
Istanbul TR
IST19:55
Madrid - Istanbul
Turkish Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Turkish Airlines TK 1358
  Madrid. ES
  MAD 14:30
  4h 25m
  1688 Miles
  Istanbul. TR
  IST 19:55
  Airbus A321neo
  Operated by Turkish Airlines
Madrid ES
MAD18:45
4h 10m
No stops
Istanbul TR
IST23:55
Madrid - Istanbul
Turkish Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Turkish Airlines TK 1860
  Madrid. ES
  MAD 18:45
  4h 10m
  1688 Miles
  Istanbul. TR
  IST 23:55
  Airbus A330-300 Passenger
  Operated by Turkish Airlines
Madrid ES
MAD12:40
6h 20m
1 Stop
Istanbul TR
IST20:00
Madrid - Istanbul
Aegean Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Aegean Airlines A3 701
  Madrid. ES
  MAD 12:40
  3h 25m
  1485 Miles
  Athens. GR
  ATH 17:05
  Airbus A321neo
  Operated by Aegean Airlines
2. Flight 2Aegean Airlines A3 994
  Athens. GR
  ATH 18:30
  1h 30m
  345 Miles
  Istanbul. TR
  IST 20:00
  Airbus A320 Passenger
  Operated by Aegean Airlines
Madrid ES
MAD14:55
6h 55m
1 Stop
Istanbul TR
IST22:50
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Lufthansa LH 1803
  Madrid. ES
  MAD 14:55
  2h 30m
  935 Miles
  Munich. DE
  MUC 17:25
  Airbus A320neo
  Operated by Lufthansa
2. Flight 2Turkish Airlines TK 1636
  Munich. DE
  MUC 19:00
  2h 50m
  967 Miles
  Istanbul. TR
  IST 22:50
  Boeing 737-900 Passenger/BBJ3 (winglets)
  Operated by Turkish Airlines
Madrid ES
MAD15:30
7h 10m
1 Stop
Istanbul TR
IST23:40
Madrid - Istanbul
LOT Polish Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1LOT Polish Airlines LO 434
  Madrid. ES
  MAD 15:30
  3h 35m
  1419 Miles
  Warsaw. PL
  WAW 19:05
  Boeing 737 MAX 8 Passenger / BBJ MAX 8 / Boeing 737 MAX 200
  Operated by LOT Polish Airlines
2. Flight 2LOT Polish Airlines LO 137
  Warsaw. PL
  WAW 19:55
  2h 45m
  842 Miles
  Istanbul. TR
  IST 23:40
  Embraer 195 and Legacy 1000
  Operated by LOT Polish Airlines
Madrid ES
MAD13:00
7h 20m
1 Stop
Istanbul TR
IST21:20
Madrid - Istanbul
Lufthansa
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Lufthansa LH 1113
  Madrid. ES
  MAD 13:00
  2h 35m
  888 Miles
  Frankfurt. DE
  FRA 15:35
  Airbus A321 Passenger
  Operated by Lufthansa
2. Flight 2Lufthansa LH 1304
  Frankfurt. DE
  FRA 17:20
  3h 0m
  1148 Miles
  Istanbul. TR
  IST 21:20
  Airbus A320 Passenger (sharklets)
  Operated by Lufthansa
Madrid ES
MAD10:10
7h 55m
1 Stop
Istanbul TR
IST19:05
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Swiss LX 2021
  Madrid. ES
  MAD 10:10
  2h 15m
  774 Miles
  Zurich. CH
  ZRH 12:25
  Airbus A220-300 Passenger
  Operated by Swiss
2. Flight 2Turkish Airlines TK 1914
  Zurich. CH
  ZRH 15:00
  3h 5m
  1087 Miles
  Istanbul. TR
  IST 19:05
  Airbus A321neo
  Operated by Turkish Airlines
Madrid ES
MAD11:50
8h 30m
2 Stops
Istanbul TR
IST21:20
Madrid - Istanbul
Lufthansa
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Lufthansa LH 1801
  Madrid. ES
  MAD 11:50
  2h 30m
  935 Miles
  Munich. DE
  MUC 14:20
  Airbus A320 Passenger (sharklets)
  Operated by Lufthansa
2. Flight 2Lufthansa LH 111
  Munich. DE
  MUC 15:00
  1h 0m
  187 Miles
  Frankfurt. DE
  FRA 16:00
  Airbus A320 Passenger
  Operated by Lufthansa
3. Flight 3Lufthansa LH 1304
  Frankfurt. DE
  FRA 17:20
  3h 0m
  1148 Miles
  Istanbul. TR
  IST 21:20
  
  Operated by Lufthansa
Madrid ES
MAD06:20
8h 30m
1 Stop
Istanbul TR
IST15:50
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Brussels Airlines SN 3732
  Madrid. ES
  MAD 06:20
  2h 15m
  822 Miles
  Brussels. BE
  BRU 08:35
  Airbus A320 Passenger
  Operated by Brussels Airlines
2. Flight 2Turkish Airlines TK 1938
  Brussels. BE
  BRU 11:20
  3h 30m
  1338 Miles
  Istanbul. TR
  IST 15:50
  Airbus A321 Passenger (sharklets)
  Operated by Turkish Airlines
Madrid ES
MAD13:35
8h 50m
1 Stop
Istanbul TR
IST23:25
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1TAP Air Portugal TP 1013
  Madrid. ES
  MAD 13:35
  1h 20m
  320 Miles
  Lisbon. PT
  LIS 13:55
  Airbus A320 Passenger
  Operated by TAP Air Portugal
2. Flight 2Turkish Airlines TK 1760
  Lisbon. PT
  LIS 16:25
  5h 0m
  2006 Miles
  Istanbul. TR
  IST 23:25
  Airbus A321neo
  Operated by Turkish Airlines
Madrid ES
MAD12:40
8h 55m
2 Stops
Istanbul TR
IST22:35
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Aegean Airlines A3 701
  Madrid. ES
  MAD 12:40
  3h 25m
  1485 Miles
  Athens. GR
  ATH 17:05
  Airbus A321neo
  Operated by Aegean Airlines
2. Flight 2Aegean Airlines A3 122
  Athens. GR
  ATH 18:05
  0h 55m
  186 Miles
  Thessaloniki. GR
  SKG 19:00
  Airbus A320 Passenger
  Operated by Aegean Airlines
3. Flight 3Turkish Airlines TK 1894
  Thessaloniki. GR
  SKG 21:05
  1h 30m
  307 Miles
  Istanbul. TR
  IST 22:35
  
  Operated by Turkish Airlines
Madrid ES
MAD12:40
9h 15m
2 Stops
Istanbul TR
IST22:55
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Brussels Airlines SN 3722
  Madrid. ES
  MAD 12:40
  2h 15m
  822 Miles
  Brussels. BE
  BRU 14:55
  Airbus A320 Passenger
  Operated by Brussels Airlines
2. Flight 2Brussels Airlines SN 2555
  Brussels. BE
  BRU 15:20
  1h 55m
  716 Miles
  Warsaw. PL
  WAW 17:15
  Airbus A319 Passenger
  Operated by Brussels Airlines
3. Flight 3Turkish Airlines TK 1766
  Warsaw. PL
  WAW 19:20
  2h 35m
  842 Miles
  Istanbul. TR
  IST 22:55
  
  Operated by Turkish Airlines
Madrid ES
MAD06:20
9h 25m
2 Stops
Istanbul TR
IST16:45
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Brussels Airlines SN 3732
  Madrid. ES
  MAD 06:20
  2h 15m
  822 Miles
  Brussels. BE
  BRU 08:35
  Airbus A320 Passenger
  Operated by Brussels Airlines
2. Flight 2LOT Polish Airlines LO 236
  Brussels. BE
  BRU 10:15
  2h 5m
  716 Miles
  Warsaw. PL
  WAW 12:20
  Embraer 170
  Operated by LOT Polish Airlines
3. Flight 3LOT Polish Airlines LO 135
  Warsaw. PL
  WAW 12:55
  2h 50m
  842 Miles
  Istanbul. TR
  IST 16:45
  
  Operated by LOT Polish Airlines
Madrid ES
MAD12:40
9h 40m
2 Stops
Istanbul TR
IST23:20
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Brussels Airlines SN 3722
  Madrid. ES
  MAD 12:40
  2h 15m
  822 Miles
  Brussels. BE
  BRU 14:55
  Airbus A320 Passenger
  Operated by Brussels Airlines
2. Flight 2Brussels Airlines SN 2905
  Brussels. BE
  BRU 15:35
  1h 45m
  577 Miles
  Vienna. AT
  VIE 17:20
  Airbus A319 Passenger
  Operated by Brussels Airlines
3. Flight 3Turkish Airlines TK 1888
  Vienna. AT
  VIE 19:55
  2h 25m
  765 Miles
  Istanbul. TR
  IST 23:20
  
  Operated by Turkish Airlines
Madrid ES
MAD05:55
9h 50m
2 Stops
Istanbul TR
IST16:45
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Lufthansa LH 1121
  Madrid. ES
  MAD 05:55
  2h 35m
  888 Miles
  Frankfurt. DE
  FRA 08:30
  Airbus A321 Passenger
  Operated by Lufthansa
2. Flight 2LOT Polish Airlines LO 382
  Frankfurt. DE
  FRA 10:25
  1h 45m
  559 Miles
  Warsaw. PL
  WAW 12:10
  Embraer 195 and Legacy 1000
  Operated by LOT Polish Airlines
3. Flight 3LOT Polish Airlines LO 135
  Warsaw. PL
  WAW 12:55
  2h 50m
  842 Miles
  Istanbul. TR
  IST 16:45
  
  Operated by LOT Polish Airlines
Madrid ES
MAD12:40
10h 0m
2 Stops
Istanbul TR
IST23:40
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Brussels Airlines SN 3722
  Madrid. ES
  MAD 12:40
  2h 15m
  822 Miles
  Brussels. BE
  BRU 14:55
  Airbus A320 Passenger
  Operated by Brussels Airlines
2. Flight 2Brussels Airlines SN 2555
  Brussels. BE
  BRU 15:20
  1h 55m
  716 Miles
  Warsaw. PL
  WAW 17:15
  Airbus A319 Passenger
  Operated by Brussels Airlines
3. Flight 3LOT Polish Airlines LO 137
  Warsaw. PL
  WAW 19:55
  2h 45m
  842 Miles
  Istanbul. TR
  IST 23:40
  
  Operated by LOT Polish Airlines
Madrid ES
MAD12:40
10h 0m
2 Stops
Istanbul TR
IST23:40
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Brussels Airlines SN 3722
  Madrid. ES
  MAD 12:40
  2h 15m
  822 Miles
  Brussels. BE
  BRU 14:55
  Airbus A320 Passenger
  Operated by Brussels Airlines
2. Flight 2Brussels Airlines SN 2259
  Brussels. BE
  BRU 15:50
  1h 30m
  471 Miles
  Copenhagen. DK
  CPH 17:20
  Airbus A320 Passenger
  Operated by Brussels Airlines
3. Flight 3Turkish Airlines TK 1786
  Copenhagen. DK
  CPH 19:20
  3h 20m
  1236 Miles
  Istanbul. TR
  IST 23:40
  
  Operated by Turkish Airlines
Madrid ES
MAD06:35
10h 0m
2 Stops
Istanbul TR
IST17:35
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1TAP Air Portugal TP 1023
  Madrid. ES
  MAD 06:35
  1h 20m
  320 Miles
  Lisbon. PT
  LIS 06:55
  Airbus A320 Passenger
  Operated by TAP Air Portugal
2. Flight 2TAP Air Portugal TP 1270
  Lisbon. PT
  LIS 08:10
  3h 25m
  1440 Miles
  Vienna. AT
  VIE 12:35
  Airbus A320neo
  Operated by TAP Air Portugal
3. Flight 3Turkish Airlines TK 1886
  Vienna. AT
  VIE 14:10
  2h 25m
  765 Miles
  Istanbul. TR
  IST 17:35
  
  Operated by Turkish Airlines
Madrid ES
MAD17:35
10h 15m
2 Stops
Istanbul TR
IST04:50
+1 day/s
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Brussels Airlines SN 3728
  Madrid. ES
  MAD 17:35
  2h 20m
  822 Miles
  Brussels. BE
  BRU 19:55
  Airbus A320neo
  Operated by Brussels Airlines
2. Flight 2Brussels Airlines SN 2265
  Brussels. BE
  BRU 21:05
  1h 30m
  471 Miles
  Copenhagen. DK
  CPH 22:35
  Airbus A320 Passenger
  Operated by Brussels Airlines
3. Flight 3Turkish Airlines TK 1788
  Copenhagen. DK
  CPH 00:35
  3h 15m
  1236 Miles
  Istanbul. TR
  IST 04:50
  
  Operated by Turkish Airlines
Madrid ES
MAD11:05
10h 25m
2 Stops
Istanbul TR
IST22:30
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1TAP Air Portugal TP 1011
  Madrid. ES
  MAD 11:05
  1h 20m
  320 Miles
  Lisbon. PT
  LIS 11:25
  Airbus A320 Passenger
  Operated by TAP Air Portugal
2. Flight 2TAP Air Portugal TP 932
  Lisbon. PT
  LIS 13:30
  2h 45m
  1076 Miles
  Zurich. CH
  ZRH 17:15
  Airbus A320neo
  Operated by TAP Air Portugal
3. Flight 3Turkish Airlines TK 1910
  Zurich. CH
  ZRH 18:30
  3h 0m
  1087 Miles
  Istanbul. TR
  IST 22:30
  
  Operated by Turkish Airlines
Madrid ES
MAD06:35
10h 55m
2 Stops
Istanbul TR
IST18:30
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1TAP Air Portugal TP 1023
  Madrid. ES
  MAD 06:35
  1h 20m
  320 Miles
  Lisbon. PT
  LIS 06:55
  Airbus A320 Passenger
  Operated by TAP Air Portugal
2. Flight 2TAP Air Portugal TP 552
  Lisbon. PT
  LIS 08:40
  3h 5m
  1239 Miles
  Munich. DE
  MUC 12:45
  Airbus A320neo
  Operated by TAP Air Portugal
3. Flight 3Turkish Airlines TK 1634
  Munich. DE
  MUC 14:40
  2h 50m
  967 Miles
  Istanbul. TR
  IST 18:30
  
  Operated by Turkish Airlines
Madrid ES
MAD11:05
11h 15m
2 Stops
Istanbul TR
IST23:20
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1TAP Air Portugal TP 1011
  Madrid. ES
  MAD 11:05
  1h 20m
  320 Miles
  Lisbon. PT
  LIS 11:25
  Airbus A320 Passenger
  Operated by TAP Air Portugal
2. Flight 2TAP Air Portugal TP 942
  Lisbon. PT
  LIS 14:05
  2h 25m
  934 Miles
  Geneva. CH
  GVA 17:30
  Airbus A320 Passenger
  Operated by TAP Air Portugal
3. Flight 3Turkish Airlines TK 1920
  Geneva. CH
  GVA 19:05
  3h 15m
  1182 Miles
  Istanbul. TR
  IST 23:20
  
  Operated by Turkish Airlines
Madrid ES
MAD11:05
11h 35m
2 Stops
Istanbul TR
IST23:40
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1TAP Air Portugal TP 1011
  Madrid. ES
  MAD 11:05
  1h 20m
  320 Miles
  Lisbon. PT
  LIS 11:25
  Airbus A320 Passenger
  Operated by TAP Air Portugal
2. Flight 2TAP Air Portugal TP 1928
  Lisbon. PT
  LIS 14:00
  1h 0m
  172 Miles
  Porto. PT
  OPO 15:00
  Embraer 190
  Operated by TAP Air Portugal
3. Flight 3Turkish Airlines TK 1452
  Porto. PT
  OPO 17:00
  4h 40m
  1939 Miles
  Istanbul. TR
  IST 23:40
  
  Operated by Turkish Airlines
Madrid ES
MAD06:20
11h 45m
2 Stops
Istanbul TR
IST19:05
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Brussels Airlines SN 3732
  Madrid. ES
  MAD 06:20
  2h 15m
  822 Miles
  Brussels. BE
  BRU 08:35
  Airbus A320 Passenger
  Operated by Brussels Airlines
2. Flight 2Brussels Airlines SN 2623
  Brussels. BE
  BRU 11:05
  1h 15m
  301 Miles
  Hamburg. DE
  HAM 12:20
  Airbus A319 Passenger
  Operated by Brussels Airlines
3. Flight 3Turkish Airlines TK 1666
  Hamburg. DE
  HAM 14:45
  3h 20m
  1223 Miles
  Istanbul. TR
  IST 19:05
  
  Operated by Turkish Airlines