Flights from Madrid (MAD) to Istanbul (IST)

Flight schedules from Madrid to Istanbul with Star Alliance member carriers

Please note that the flight schedules of our member carriers are subject to change on short notice. We recommend using our member airlines information page. for the latest flight updates, details on booking flexibility, as well as specific Frequent Flyer Program information.

Outbound (18)

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Madrid ES
MAD12:00
4h 15m
No stops
Istanbul TR
IST18:15
Madrid - Istanbul
Turkish Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Turkish Airlines TK 1858
  Madrid. ES
  MAD 12:00
  4h 15m
  1688 Miles
  Istanbul. TR
  IST 18:15
  Airbus A330-300 Passenger
  Operated by Turkish Airlines
Madrid ES
MAD14:55
4h 15m
No stops
Istanbul TR
IST21:10
Madrid - Istanbul
Turkish Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Turkish Airlines TK 1358
  Madrid. ES
  MAD 14:55
  4h 15m
  1688 Miles
  Istanbul. TR
  IST 21:10
  Airbus A321neo
  Operated by Turkish Airlines
Madrid ES
MAD17:40
4h 25m
No stops
Istanbul TR
IST00:05
+1 day/s
Madrid - Istanbul
Turkish Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Turkish Airlines TK 1860
  Madrid. ES
  MAD 17:40
  4h 25m
  1688 Miles
  Istanbul. TR
  IST 00:05
  Airbus A321neo
  Operated by Turkish Airlines
Madrid ES
MAD13:05
5h 55m
1 Stop
Istanbul TR
IST21:00
Madrid - Istanbul
Aegean Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Aegean Airlines A3 701
  Madrid. ES
  MAD 13:05
  3h 25m
  1485 Miles
  Athens. GR
  ATH 17:30
  Airbus A321neo
  Operated by Aegean Airlines
2. Flight 2Aegean Airlines A3 994
  Athens. GR
  ATH 18:30
  1h 30m
  345 Miles
  Istanbul. TR
  IST 21:00
  Airbus A321neo
  Operated by Aegean Airlines
Madrid ES
MAD08:25
6h 40m
1 Stop
Istanbul TR
IST17:05
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Lufthansa LH 1123
  Madrid. ES
  MAD 08:25
  2h 35m
  888 Miles
  Frankfurt. DE
  FRA 11:00
  Airbus A320 Passenger
  Operated by Lufthansa
2. Flight 2Turkish Airlines TK 1588
  Frankfurt. DE
  FRA 11:55
  3h 10m
  1148 Miles
  Istanbul. TR
  IST 17:05
  Airbus A330-300 Passenger
  Operated by Turkish Airlines
Madrid ES
MAD15:30
7h 10m
1 Stop
Istanbul TR
IST00:40
+1 day/s
Madrid - Istanbul
LOT Polish Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1LOT Polish Airlines LO 434
  Madrid. ES
  MAD 15:30
  3h 35m
  1419 Miles
  Warsaw. PL
  WAW 19:05
  Boeing 737 MAX 8 Passenger / BBJ MAX 8 / Boeing 737 MAX 200
  Operated by LOT Polish Airlines
2. Flight 2LOT Polish Airlines LO 137
  Warsaw. PL
  WAW 19:55
  2h 45m
  842 Miles
  Istanbul. TR
  IST 00:40
  Embraer 195 and Legacy 1000
  Operated by LOT Polish Airlines
Madrid ES
MAD08:25
7h 40m
1 Stop
Istanbul TR
IST18:05
Madrid - Istanbul
Lufthansa
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Lufthansa LH 1123
  Madrid. ES
  MAD 08:25
  2h 35m
  888 Miles
  Frankfurt. DE
  FRA 11:00
  Airbus A320 Passenger
  Operated by Lufthansa
2. Flight 2Lufthansa LH 1298
  Frankfurt. DE
  FRA 13:00
  3h 5m
  1148 Miles
  Istanbul. TR
  IST 18:05
  Airbus A320neo
  Operated by Lufthansa
Madrid ES
MAD10:05
7h 45m
1 Stop
Istanbul TR
IST19:50
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Swiss LX 2027
  Madrid. ES
  MAD 10:05
  2h 15m
  774 Miles
  Zurich. CH
  ZRH 12:20
  Airbus A220-100 Passenger
  Operated by Swiss
2. Flight 2Turkish Airlines TK 1914
  Zurich. CH
  ZRH 14:50
  3h 0m
  1087 Miles
  Istanbul. TR
  IST 19:50
  Airbus A321 Passenger (sharklets)
  Operated by Turkish Airlines
Madrid ES
MAD06:25
8h 15m
2 Stops
Istanbul TR
IST16:40
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Brussels Airlines SN 3732
  Madrid. ES
  MAD 06:25
  2h 25m
  822 Miles
  Brussels. BE
  BRU 08:50
  Airbus A319 Passenger
  Operated by Brussels Airlines
2. Flight 2Brussels Airlines SN 2623
  Brussels. BE
  BRU 09:35
  1h 15m
  301 Miles
  Hamburg. DE
  HAM 10:50
  Airbus A319 Passenger
  Operated by Brussels Airlines
3. Flight 3Turkish Airlines TK 1662
  Hamburg. DE
  HAM 11:30
  3h 10m
  1223 Miles
  Istanbul. TR
  IST 16:40
  
  Operated by Turkish Airlines
Madrid ES
MAD07:25
8h 40m
2 Stops
Istanbul TR
IST18:05
Madrid - Istanbul
Lufthansa
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Lufthansa LH 1807
  Madrid. ES
  MAD 07:25
  2h 35m
  935 Miles
  Munich. DE
  MUC 10:00
  Airbus A321neo
  Operated by Lufthansa
2. Flight 2Lufthansa LH 103
  Munich. DE
  MUC 11:00
  1h 5m
  187 Miles
  Frankfurt. DE
  FRA 12:05
  Airbus A321 Passenger
  Operated by Lufthansa
3. Flight 3Lufthansa LH 1298
  Frankfurt. DE
  FRA 13:00
  3h 5m
  1148 Miles
  Istanbul. TR
  IST 18:05
  
  Operated by Lufthansa
Madrid ES
MAD06:25
8h 40m
1 Stop
Istanbul TR
IST17:05
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Brussels Airlines SN 3732
  Madrid. ES
  MAD 06:25
  2h 25m
  822 Miles
  Brussels. BE
  BRU 08:50
  Airbus A319 Passenger
  Operated by Brussels Airlines
2. Flight 2Turkish Airlines TK 1938
  Brussels. BE
  BRU 11:40
  3h 25m
  1338 Miles
  Istanbul. TR
  IST 17:05
  Boeing 737-800 Passenger/BBJ2 (winglets)
  Operated by Turkish Airlines
Madrid ES
MAD10:05
8h 55m
2 Stops
Istanbul TR
IST21:00
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Swiss LX 2027
  Madrid. ES
  MAD 10:05
  2h 15m
  774 Miles
  Zurich. CH
  ZRH 12:20
  Airbus A220-100 Passenger
  Operated by Swiss
2. Flight 2Swiss LX 1838
  Zurich. CH
  ZRH 13:00
  2h 40m
  1024 Miles
  Athens. GR
  ATH 16:40
  Airbus A320 Passenger
  Operated by Swiss
3. Flight 3Aegean Airlines A3 994
  Athens. GR
  ATH 18:30
  1h 30m
  345 Miles
  Istanbul. TR
  IST 21:00
  
  Operated by Aegean Airlines
Madrid ES
MAD13:05
9h 10m
2 Stops
Istanbul TR
IST00:15
+1 day/s
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Aegean Airlines A3 701
  Madrid. ES
  MAD 13:05
  3h 25m
  1485 Miles
  Athens. GR
  ATH 17:30
  Airbus A321neo
  Operated by Aegean Airlines
2. Flight 2Aegean Airlines A3 126
  Athens. GR
  ATH 19:55
  0h 55m
  186 Miles
  Thessaloniki. GR
  SKG 20:50
  Airbus A320neo
  Operated by Aegean Airlines
3. Flight 3Turkish Airlines TK 1894
  Thessaloniki. GR
  SKG 21:45
  1h 30m
  307 Miles
  Istanbul. TR
  IST 00:15
  
  Operated by Turkish Airlines
Madrid ES
MAD13:05
9h 10m
2 Stops
Istanbul TR
IST00:15
+1 day/s
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Aegean Airlines A3 701
  Madrid. ES
  MAD 13:05
  3h 25m
  1485 Miles
  Athens. GR
  ATH 17:30
  Airbus A321neo
  Operated by Aegean Airlines
2. Flight 2Aegean Airlines A3 124
  Athens. GR
  ATH 19:00
  0h 50m
  186 Miles
  Thessaloniki. GR
  SKG 19:50
  Airbus A320 Passenger
  Operated by Aegean Airlines
3. Flight 3Turkish Airlines TK 1894
  Thessaloniki. GR
  SKG 21:45
  1h 30m
  307 Miles
  Istanbul. TR
  IST 00:15
  
  Operated by Turkish Airlines
Madrid ES
MAD06:25
9h 10m
2 Stops
Istanbul TR
IST17:35
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Brussels Airlines SN 3732
  Madrid. ES
  MAD 06:25
  2h 25m
  822 Miles
  Brussels. BE
  BRU 08:50
  Airbus A319 Passenger
  Operated by Brussels Airlines
2. Flight 2Brussels Airlines SN 2553
  Brussels. BE
  BRU 09:25
  1h 50m
  716 Miles
  Warsaw. PL
  WAW 11:15
  Airbus A319 Passenger
  Operated by Brussels Airlines
3. Flight 3LOT Polish Airlines LO 135
  Warsaw. PL
  WAW 12:50
  2h 45m
  842 Miles
  Istanbul. TR
  IST 17:35
  
  Operated by LOT Polish Airlines
Madrid ES
MAD12:10
9h 55m
2 Stops
Istanbul TR
IST00:05
+1 day/s
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1TAP Air Portugal TP 1013
  Madrid. ES
  MAD 12:10
  1h 20m
  320 Miles
  Lisbon. PT
  LIS 12:30
  Airbus A320 Passenger
  Operated by TAP Air Portugal
2. Flight 2TAP Air Portugal TP 1928
  Lisbon. PT
  LIS 14:00
  1h 0m
  172 Miles
  Porto. PT
  OPO 15:00
  Embraer 190
  Operated by TAP Air Portugal
3. Flight 3Turkish Airlines TK 1452
  Porto. PT
  OPO 16:25
  4h 40m
  1939 Miles
  Istanbul. TR
  IST 00:05
  
  Operated by Turkish Airlines
Madrid ES
MAD06:25
11h 5m
2 Stops
Istanbul TR
IST19:30
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Brussels Airlines SN 3732
  Madrid. ES
  MAD 06:25
  2h 25m
  822 Miles
  Brussels. BE
  BRU 08:50
  Airbus A319 Passenger
  Operated by Brussels Airlines
2. Flight 2Brussels Airlines SN 2257
  Brussels. BE
  BRU 09:50
  1h 35m
  471 Miles
  Copenhagen. DK
  CPH 11:25
  Airbus A319 Passenger
  Operated by Brussels Airlines
3. Flight 3Turkish Airlines TK 1782
  Copenhagen. DK
  CPH 14:10
  3h 20m
  1236 Miles
  Istanbul. TR
  IST 19:30
  
  Operated by Turkish Airlines
Madrid ES
MAD06:25
12h 35m
2 Stops
Istanbul TR
IST21:00
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Brussels Airlines SN 3732
  Madrid. ES
  MAD 06:25
  2h 25m
  822 Miles
  Brussels. BE
  BRU 08:50
  Airbus A319 Passenger
  Operated by Brussels Airlines
2. Flight 2Aegean Airlines A3 621
  Brussels. BE
  BRU 11:45
  3h 0m
  1313 Miles
  Athens. GR
  ATH 15:45
  Airbus A320neo
  Operated by Aegean Airlines
3. Flight 3Aegean Airlines A3 994
  Athens. GR
  ATH 18:30
  1h 30m
  345 Miles
  Istanbul. TR
  IST 21:00
  
  Operated by Aegean Airlines