Flights from Madrid (MAD) to Istanbul (IST)

Flight schedules from Madrid to Istanbul with Star Alliance member carriers

Please note that the flight schedules of our member carriers are subject to change on short notice. We recommend using our member airlines information page. for the latest flight updates, details on booking flexibility, as well as specific Frequent Flyer Program information.

Outbound (27)

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Madrid ES
MAD07:40
4h 20m
No stops
Istanbul TR
IST13:00
Madrid - Istanbul
Turkish Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Turkish Airlines TK 1360
  Madrid. ES
  MAD 07:40
  4h 20m
  1688 Miles
  Istanbul. TR
  IST 13:00
  Airbus A321 Passenger (sharklets)
  Operated by Turkish Airlines
Madrid ES
MAD12:00
4h 15m
No stops
Istanbul TR
IST17:15
Madrid - Istanbul
Turkish Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Turkish Airlines TK 1858
  Madrid. ES
  MAD 12:00
  4h 15m
  1688 Miles
  Istanbul. TR
  IST 17:15
  Airbus A330-300 Passenger
  Operated by Turkish Airlines
Madrid ES
MAD14:30
4h 25m
No stops
Istanbul TR
IST19:55
Madrid - Istanbul
Turkish Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Turkish Airlines TK 1358
  Madrid. ES
  MAD 14:30
  4h 25m
  1688 Miles
  Istanbul. TR
  IST 19:55
  Airbus A321neo
  Operated by Turkish Airlines
Madrid ES
MAD18:45
4h 10m
No stops
Istanbul TR
IST23:55
Madrid - Istanbul
Turkish Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Turkish Airlines TK 1860
  Madrid. ES
  MAD 18:45
  4h 10m
  1688 Miles
  Istanbul. TR
  IST 23:55
  Airbus A330-200 Passenger
  Operated by Turkish Airlines
Madrid ES
MAD12:40
6h 20m
1 Stop
Istanbul TR
IST20:00
Madrid - Istanbul
Aegean Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Aegean Airlines A3 701
  Madrid. ES
  MAD 12:40
  3h 25m
  1485 Miles
  Athens. GR
  ATH 17:05
  Airbus A321neo
  Operated by Aegean Airlines
2. Flight 2Aegean Airlines A3 994
  Athens. GR
  ATH 18:30
  1h 30m
  345 Miles
  Istanbul. TR
  IST 20:00
  Airbus A320 Passenger
  Operated by Aegean Airlines
Madrid ES
MAD15:30
7h 10m
1 Stop
Istanbul TR
IST23:40
Madrid - Istanbul
LOT Polish Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1LOT Polish Airlines LO 434
  Madrid. ES
  MAD 15:30
  3h 35m
  1419 Miles
  Warsaw. PL
  WAW 19:05
  Boeing 737 MAX 8 Passenger / BBJ MAX 8 / Boeing 737 MAX 200
  Operated by LOT Polish Airlines
2. Flight 2LOT Polish Airlines LO 137
  Warsaw. PL
  WAW 19:55
  2h 45m
  842 Miles
  Istanbul. TR
  IST 23:40
  Embraer 195 and Legacy 1000
  Operated by LOT Polish Airlines
Madrid ES
MAD13:00
7h 20m
1 Stop
Istanbul TR
IST21:20
Madrid - Istanbul
Lufthansa
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Lufthansa LH 1113
  Madrid. ES
  MAD 13:00
  2h 35m
  888 Miles
  Frankfurt. DE
  FRA 15:35
  Airbus A320 Passenger (sharklets)
  Operated by Lufthansa
2. Flight 2Lufthansa LH 1304
  Frankfurt. DE
  FRA 17:20
  3h 0m
  1148 Miles
  Istanbul. TR
  IST 21:20
  Airbus A321 Passenger
  Operated by Lufthansa
Madrid ES
MAD01:20
7h 30m
1 Stop
Istanbul TR
IST09:50
Madrid - Istanbul
Aegean Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Aegean Airlines A3 703
  Madrid. ES
  MAD 01:20
  3h 35m
  1485 Miles
  Athens. GR
  ATH 05:55
  Airbus A320 Passenger
  Operated by Aegean Airlines
2. Flight 2Aegean Airlines A3 990
  Athens. GR
  ATH 08:20
  1h 30m
  345 Miles
  Istanbul. TR
  IST 09:50
  Airbus A320neo
  Operated by Aegean Airlines
Madrid ES
MAD14:55
7h 35m
1 Stop
Istanbul TR
IST23:30
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Lufthansa LH 1803
  Madrid. ES
  MAD 14:55
  2h 30m
  935 Miles
  Munich. DE
  MUC 17:25
  Airbus A319 Passenger
  Operated by Lufthansa
2. Flight 2Turkish Airlines TK 1636
  Munich. DE
  MUC 19:40
  2h 50m
  967 Miles
  Istanbul. TR
  IST 23:30
  Airbus A321 Passenger (sharklets)
  Operated by Turkish Airlines
Madrid ES
MAD08:25
7h 35m
1 Stop
Istanbul TR
IST17:00
Madrid - Istanbul
Lufthansa
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Lufthansa LH 1123
  Madrid. ES
  MAD 08:25
  2h 35m
  888 Miles
  Frankfurt. DE
  FRA 11:00
  Airbus A321 Passenger
  Operated by Lufthansa
2. Flight 2Lufthansa LH 1300
  Frankfurt. DE
  FRA 13:00
  3h 0m
  1148 Miles
  Istanbul. TR
  IST 17:00
  Airbus A320neo
  Operated by Lufthansa
Madrid ES
MAD10:10
7h 55m
1 Stop
Istanbul TR
IST19:05
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Swiss LX 2021
  Madrid. ES
  MAD 10:10
  2h 15m
  774 Miles
  Zurich. CH
  ZRH 12:25
  Embraer 190 E2
  Operated by Swiss
2. Flight 2Turkish Airlines TK 1914
  Zurich. CH
  ZRH 15:00
  3h 5m
  1087 Miles
  Istanbul. TR
  IST 19:05
  Airbus A321neo
  Operated by Turkish Airlines
Madrid ES
MAD11:50
8h 30m
2 Stops
Istanbul TR
IST21:20
Madrid - Istanbul
Lufthansa
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Lufthansa LH 1801
  Madrid. ES
  MAD 11:50
  2h 30m
  935 Miles
  Munich. DE
  MUC 14:20
  Airbus A320 Passenger (sharklets)
  Operated by Lufthansa
2. Flight 2Lufthansa LH 111
  Munich. DE
  MUC 15:00
  1h 0m
  187 Miles
  Frankfurt. DE
  FRA 16:00
  Airbus A320 Passenger
  Operated by Lufthansa
3. Flight 3Lufthansa LH 1304
  Frankfurt. DE
  FRA 17:20
  3h 0m
  1148 Miles
  Istanbul. TR
  IST 21:20
  
  Operated by Lufthansa
Madrid ES
MAD01:20
8h 40m
2 Stops
Istanbul TR
IST11:00
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Aegean Airlines A3 703
  Madrid. ES
  MAD 01:20
  3h 35m
  1485 Miles
  Athens. GR
  ATH 05:55
  Airbus A320 Passenger
  Operated by Aegean Airlines
2. Flight 2Aegean Airlines A3 102
  Athens. GR
  ATH 07:00
  0h 55m
  186 Miles
  Thessaloniki. GR
  SKG 07:55
  Airbus A320 Passenger
  Operated by Aegean Airlines
3. Flight 3Turkish Airlines TK 1882
  Thessaloniki. GR
  SKG 09:30
  1h 30m
  307 Miles
  Istanbul. TR
  IST 11:00
  
  Operated by Turkish Airlines
Madrid ES
MAD07:15
8h 45m
2 Stops
Istanbul TR
IST17:00
Madrid - Istanbul
Lufthansa
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Lufthansa LH 1807
  Madrid. ES
  MAD 07:15
  2h 30m
  935 Miles
  Munich. DE
  MUC 09:45
  Airbus A321neo
  Operated by Lufthansa
2. Flight 2Lufthansa LH 103
  Munich. DE
  MUC 11:00
  1h 0m
  187 Miles
  Frankfurt. DE
  FRA 12:00
  Airbus A319 Passenger
  Operated by Lufthansa
3. Flight 3Lufthansa LH 1300
  Frankfurt. DE
  FRA 13:00
  3h 0m
  1148 Miles
  Istanbul. TR
  IST 17:00
  
  Operated by Lufthansa
Madrid ES
MAD06:20
8h 45m
1 Stop
Istanbul TR
IST16:05
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Brussels Airlines SN 3732
  Madrid. ES
  MAD 06:20
  2h 15m
  822 Miles
  Brussels. BE
  BRU 08:35
  Airbus A320 Passenger
  Operated by Brussels Airlines
2. Flight 2Turkish Airlines TK 1938
  Brussels. BE
  BRU 11:35
  3h 30m
  1338 Miles
  Istanbul. TR
  IST 16:05
  Airbus A330-200 Passenger
  Operated by Turkish Airlines
Madrid ES
MAD12:40
8h 55m
2 Stops
Istanbul TR
IST22:35
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Aegean Airlines A3 701
  Madrid. ES
  MAD 12:40
  3h 25m
  1485 Miles
  Athens. GR
  ATH 17:05
  Airbus A321neo
  Operated by Aegean Airlines
2. Flight 2Aegean Airlines A3 122
  Athens. GR
  ATH 18:05
  0h 55m
  186 Miles
  Thessaloniki. GR
  SKG 19:00
  Airbus A320 Passenger
  Operated by Aegean Airlines
3. Flight 3Turkish Airlines TK 1894
  Thessaloniki. GR
  SKG 21:05
  1h 30m
  307 Miles
  Istanbul. TR
  IST 22:35
  
  Operated by Turkish Airlines
Madrid ES
MAD13:35
9h 5m
1 Stop
Istanbul TR
IST23:40
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1TAP Air Portugal TP 1013
  Madrid. ES
  MAD 13:35
  1h 25m
  320 Miles
  Lisbon. PT
  LIS 14:00
  Embraer 190
  Operated by TAP Air Portugal
2. Flight 2Turkish Airlines TK 1760
  Lisbon. PT
  LIS 16:50
  4h 50m
  2006 Miles
  Istanbul. TR
  IST 23:40
  Airbus A330-300 Passenger
  Operated by Turkish Airlines
Madrid ES
MAD06:20
9h 25m
2 Stops
Istanbul TR
IST16:45
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Brussels Airlines SN 3732
  Madrid. ES
  MAD 06:20
  2h 15m
  822 Miles
  Brussels. BE
  BRU 08:35
  Airbus A320 Passenger
  Operated by Brussels Airlines
2. Flight 2LOT Polish Airlines LO 236
  Brussels. BE
  BRU 10:15
  2h 5m
  716 Miles
  Warsaw. PL
  WAW 12:20
  Embraer 190
  Operated by LOT Polish Airlines
3. Flight 3LOT Polish Airlines LO 135
  Warsaw. PL
  WAW 12:55
  2h 50m
  842 Miles
  Istanbul. TR
  IST 16:45
  
  Operated by LOT Polish Airlines
Madrid ES
MAD05:55
9h 50m
2 Stops
Istanbul TR
IST16:45
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Lufthansa LH 1121
  Madrid. ES
  MAD 05:55
  2h 35m
  888 Miles
  Frankfurt. DE
  FRA 08:30
  Airbus A321 Passenger
  Operated by Lufthansa
2. Flight 2LOT Polish Airlines LO 382
  Frankfurt. DE
  FRA 10:25
  1h 45m
  559 Miles
  Warsaw. PL
  WAW 12:10
  Embraer 190
  Operated by LOT Polish Airlines
3. Flight 3LOT Polish Airlines LO 135
  Warsaw. PL
  WAW 12:55
  2h 50m
  842 Miles
  Istanbul. TR
  IST 16:45
  
  Operated by LOT Polish Airlines
Madrid ES
MAD06:35
10h 0m
2 Stops
Istanbul TR
IST17:35
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1TAP Air Portugal TP 1023
  Madrid. ES
  MAD 06:35
  1h 15m
  320 Miles
  Lisbon. PT
  LIS 06:50
  Airbus A321 Passenger
  Operated by TAP Air Portugal
2. Flight 2TAP Air Portugal TP 1270
  Lisbon. PT
  LIS 08:10
  3h 25m
  1440 Miles
  Vienna. AT
  VIE 12:35
  Airbus A320neo
  Operated by TAP Air Portugal
3. Flight 3Turkish Airlines TK 1886
  Vienna. AT
  VIE 14:10
  2h 25m
  765 Miles
  Istanbul. TR
  IST 17:35
  
  Operated by Turkish Airlines
Madrid ES
MAD22:45
10h 5m
2 Stops
Istanbul TR
IST09:50
+1 day/s
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1TAP Air Portugal TP 1021
  Madrid. ES
  MAD 22:45
  1h 20m
  320 Miles
  Lisbon. PT
  LIS 23:05
  Embraer 195 and Legacy 1000
  Operated by TAP Air Portugal
2. Flight 2Aegean Airlines A3 723
  Lisbon. PT
  LIS 00:35
  3h 55m
  1793 Miles
  Athens. GR
  ATH 06:30
  Airbus A321neo
  Operated by Aegean Airlines
3. Flight 3Aegean Airlines A3 990
  Athens. GR
  ATH 08:20
  1h 30m
  345 Miles
  Istanbul. TR
  IST 09:50
  
  Operated by Aegean Airlines
Madrid ES
MAD06:35
10h 55m
2 Stops
Istanbul TR
IST18:30
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1TAP Air Portugal TP 1023
  Madrid. ES
  MAD 06:35
  1h 15m
  320 Miles
  Lisbon. PT
  LIS 06:50
  Airbus A321 Passenger
  Operated by TAP Air Portugal
2. Flight 2TAP Air Portugal TP 552
  Lisbon. PT
  LIS 08:40
  3h 5m
  1239 Miles
  Munich. DE
  MUC 12:45
  Airbus A321neo
  Operated by TAP Air Portugal
3. Flight 3Turkish Airlines TK 1634
  Munich. DE
  MUC 14:40
  2h 50m
  967 Miles
  Istanbul. TR
  IST 18:30
  
  Operated by Turkish Airlines
Madrid ES
MAD06:35
11h 0m
2 Stops
Istanbul TR
IST18:35
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1TAP Air Portugal TP 1023
  Madrid. ES
  MAD 06:35
  1h 15m
  320 Miles
  Lisbon. PT
  LIS 06:50
  Airbus A321 Passenger
  Operated by TAP Air Portugal
2. Flight 2TAP Air Portugal TP 1924
  Lisbon. PT
  LIS 08:55
  1h 0m
  172 Miles
  Porto. PT
  OPO 09:55
  Airbus A320 Passenger
  Operated by TAP Air Portugal
3. Flight 3Turkish Airlines TK 1450
  Porto. PT
  OPO 11:55
  4h 40m
  1939 Miles
  Istanbul. TR
  IST 18:35
  
  Operated by Turkish Airlines
Madrid ES
MAD06:35
11h 0m
2 Stops
Istanbul TR
IST18:35
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1TAP Air Portugal TP 1023
  Madrid. ES
  MAD 06:35
  1h 15m
  320 Miles
  Lisbon. PT
  LIS 06:50
  Airbus A321 Passenger
  Operated by TAP Air Portugal
2. Flight 2TAP Air Portugal TP 1922
  Lisbon. PT
  LIS 08:05
  1h 0m
  172 Miles
  Porto. PT
  OPO 09:05
  Airbus A320neo
  Operated by TAP Air Portugal
3. Flight 3Turkish Airlines TK 1450
  Porto. PT
  OPO 11:55
  4h 40m
  1939 Miles
  Istanbul. TR
  IST 18:35
  
  Operated by Turkish Airlines
Madrid ES
MAD06:35
11h 0m
2 Stops
Istanbul TR
IST18:35
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1TAP Air Portugal TP 1023
  Madrid. ES
  MAD 06:35
  1h 15m
  320 Miles
  Lisbon. PT
  LIS 06:50
  Airbus A321 Passenger
  Operated by TAP Air Portugal
2. Flight 2TAP Air Portugal TP 1926
  Lisbon. PT
  LIS 09:40
  1h 0m
  172 Miles
  Porto. PT
  OPO 10:40
  Embraer 190
  Operated by TAP Air Portugal
3. Flight 3Turkish Airlines TK 1450
  Porto. PT
  OPO 11:55
  4h 40m
  1939 Miles
  Istanbul. TR
  IST 18:35
  
  Operated by Turkish Airlines
Madrid ES
MAD11:05
11h 15m
2 Stops
Istanbul TR
IST23:20
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1TAP Air Portugal TP 1011
  Madrid. ES
  MAD 11:05
  1h 20m
  320 Miles
  Lisbon. PT
  LIS 11:25
  Airbus A320neo
  Operated by TAP Air Portugal
2. Flight 2TAP Air Portugal TP 942
  Lisbon. PT
  LIS 14:05
  2h 25m
  934 Miles
  Geneva. CH
  GVA 17:30
  Airbus A320neo
  Operated by TAP Air Portugal
3. Flight 3Turkish Airlines TK 1920
  Geneva. CH
  GVA 19:00
  3h 20m
  1182 Miles
  Istanbul. TR
  IST 23:20
  
  Operated by Turkish Airlines
Madrid ES
MAD11:05
11h 25m
2 Stops
Istanbul TR
IST23:30
Madrid - Istanbul
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1TAP Air Portugal TP 1011
  Madrid. ES
  MAD 11:05
  1h 20m
  320 Miles
  Lisbon. PT
  LIS 11:25
  Airbus A320neo
  Operated by TAP Air Portugal
2. Flight 2TAP Air Portugal TP 1928
  Lisbon. PT
  LIS 14:20
  1h 0m
  172 Miles
  Porto. PT
  OPO 15:20
  Airbus A320 Passenger
  Operated by TAP Air Portugal
3. Flight 3Turkish Airlines TK 1452
  Porto. PT
  OPO 16:50
  4h 40m
  1939 Miles
  Istanbul. TR
  IST 23:30
  
  Operated by Turkish Airlines