Flights from Medellin (MDE) to Guayaquil (GYE)

Flight schedules from Medellin to Guayaquil with Star Alliance member carriers

Please note that the flight schedules of our member carriers are subject to change on short notice. We recommend using our member airlines information page. for the latest flight updates, details on booking flexibility, as well as specific Frequent Flyer Program information.

Outbound (25)

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Medellin CO
MDE18:29
4h 11m
1 Stop
Guayaquil EC
GYE22:40
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9375
  Medellin. CO
  MDE 18:29
  0h 55m
  145 Miles
  Bogota. CO
  BOG 19:24
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8371
  Bogota. CO
  BOG 20:40
  2h 0m
  621 Miles
  Guayaquil. EC
  GYE 22:40
  Airbus A319 Passenger
  Operated by Avianca
Medellin CO
MDE13:03
4h 12m
1 Stop
Guayaquil EC
GYE17:15
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9329
  Medellin. CO
  MDE 13:03
  0h 56m
  145 Miles
  Bogota. CO
  BOG 13:59
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8383
  Bogota. CO
  BOG 15:10
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 17:15
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE09:21
4h 27m
1 Stop
Guayaquil EC
GYE13:48
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 398
  Medellin. CO
  MDE 09:21
  1h 30m
  327 Miles
  Panama City. PA
  PTY 10:51
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 258
  Panama City. PA
  PTY 11:31
  2h 17m
  780 Miles
  Guayaquil. EC
  GYE 13:48
  Boeing 737-800 Passenger
  Operated by Copa Airlines
Medellin CO
MDE19:03
4h 34m
1 Stop
Guayaquil EC
GYE23:37
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 8415
  Medellin. CO
  MDE 19:03
  0h 56m
  145 Miles
  Bogota. CO
  BOG 19:59
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8391
  Bogota. CO
  BOG 21:32
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 23:37
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE06:39
4h 39m
1 Stop
Guayaquil EC
GYE11:18
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 209
  Medellin. CO
  MDE 06:39
  1h 30m
  327 Miles
  Panama City. PA
  PTY 08:09
  Boeing 737-700 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 273
  Panama City. PA
  PTY 09:01
  2h 17m
  780 Miles
  Guayaquil. EC
  GYE 11:18
  Boeing 737-700 Passenger
  Operated by Copa Airlines
Medellin CO
MDE09:15
4h 45m
1 Stop
Guayaquil EC
GYE14:00
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9307
  Medellin. CO
  MDE 09:15
  0h 56m
  145 Miles
  Bogota. CO
  BOG 10:11
  Airbus A319 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8389
  Bogota. CO
  BOG 12:05
  1h 55m
  621 Miles
  Guayaquil. EC
  GYE 14:00
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE12:26
4h 49m
1 Stop
Guayaquil EC
GYE17:15
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9346
  Medellin. CO
  MDE 12:26
  0h 56m
  145 Miles
  Bogota. CO
  BOG 13:22
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8383
  Bogota. CO
  BOG 15:10
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 17:15
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE08:47
5h 1m
1 Stop
Guayaquil EC
GYE13:48
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 164
  Medellin. CO
  MDE 08:47
  1h 30m
  327 Miles
  Panama City. PA
  PTY 10:17
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 258
  Panama City. PA
  PTY 11:31
  2h 17m
  780 Miles
  Guayaquil. EC
  GYE 13:48
  Boeing 737-800 Passenger
  Operated by Copa Airlines
Medellin CO
MDE18:29
5h 8m
1 Stop
Guayaquil EC
GYE23:37
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9375
  Medellin. CO
  MDE 18:29
  0h 55m
  145 Miles
  Bogota. CO
  BOG 19:24
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8391
  Bogota. CO
  BOG 21:32
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 23:37
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE08:51
5h 9m
1 Stop
Guayaquil EC
GYE14:00
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9323
  Medellin. CO
  MDE 08:51
  0h 56m
  145 Miles
  Bogota. CO
  BOG 09:47
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8389
  Bogota. CO
  BOG 12:05
  1h 55m
  621 Miles
  Guayaquil. EC
  GYE 14:00
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE15:32
5h 10m
1 Stop
Guayaquil EC
GYE20:42
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 154
  Medellin. CO
  MDE 15:32
  1h 30m
  327 Miles
  Panama City. PA
  PTY 17:02
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 213
  Panama City. PA
  PTY 18:25
  2h 17m
  780 Miles
  Guayaquil. EC
  GYE 20:42
  Boeing 737 MAX 9 Passenger / BBJ MAX 9
  Operated by Copa Airlines
Medellin CO
MDE17:19
5h 21m
1 Stop
Guayaquil EC
GYE22:40
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9343
  Medellin. CO
  MDE 17:19
  0h 56m
  145 Miles
  Bogota. CO
  BOG 18:15
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8371
  Bogota. CO
  BOG 20:40
  2h 0m
  621 Miles
  Guayaquil. EC
  GYE 22:40
  Airbus A319 Passenger
  Operated by Avianca
Medellin CO
MDE12:15
5h 21m
1 Stop
Guayaquil EC
GYE17:36
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 506
  Medellin. CO
  MDE 12:15
  1h 30m
  327 Miles
  Panama City. PA
  PTY 13:45
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 378
  Panama City. PA
  PTY 15:19
  2h 17m
  780 Miles
  Guayaquil. EC
  GYE 17:36
  Boeing 737-800 Passenger
  Operated by Copa Airlines
Medellin CO
MDE11:52
5h 23m
1 Stop
Guayaquil EC
GYE17:15
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9339
  Medellin. CO
  MDE 11:52
  0h 56m
  145 Miles
  Bogota. CO
  BOG 12:48
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8383
  Bogota. CO
  BOG 15:10
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 17:15
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE18:18
5h 24m
1 Stop
Guayaquil EC
GYE23:42
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 157
  Medellin. CO
  MDE 18:18
  1h 28m
  327 Miles
  Panama City. PA
  PTY 19:46
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 301
  Panama City. PA
  PTY 21:25
  2h 17m
  780 Miles
  Guayaquil. EC
  GYE 23:42
  Boeing 737-800 Passenger
  Operated by Copa Airlines
Medellin CO
MDE08:33
5h 27m
1 Stop
Guayaquil EC
GYE14:00
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 8451
  Medellin. CO
  MDE 08:33
  0h 56m
  145 Miles
  Bogota. CO
  BOG 09:29
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8389
  Bogota. CO
  BOG 12:05
  1h 55m
  621 Miles
  Guayaquil. EC
  GYE 14:00
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE08:21
5h 39m
1 Stop
Guayaquil EC
GYE14:00
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9463
  Medellin. CO
  MDE 08:21
  0h 56m
  145 Miles
  Bogota. CO
  BOG 09:17
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8389
  Bogota. CO
  BOG 12:05
  1h 55m
  621 Miles
  Guayaquil. EC
  GYE 14:00
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE11:32
5h 43m
1 Stop
Guayaquil EC
GYE17:15
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9349
  Medellin. CO
  MDE 11:32
  0h 55m
  145 Miles
  Bogota. CO
  BOG 12:27
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8383
  Bogota. CO
  BOG 15:10
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 17:15
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE05:31
5h 47m
1 Stop
Guayaquil EC
GYE11:18
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 151
  Medellin. CO
  MDE 05:31
  1h 24m
  327 Miles
  Panama City. PA
  PTY 06:55
  Boeing 737-700 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 273
  Panama City. PA
  PTY 09:01
  2h 17m
  780 Miles
  Guayaquil. EC
  GYE 11:18
  Boeing 737-700 Passenger
  Operated by Copa Airlines
Medellin CO
MDE16:43
5h 57m
1 Stop
Guayaquil EC
GYE22:40
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9313
  Medellin. CO
  MDE 16:43
  0h 58m
  145 Miles
  Bogota. CO
  BOG 17:41
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8371
  Bogota. CO
  BOG 20:40
  2h 0m
  621 Miles
  Guayaquil. EC
  GYE 22:40
  Airbus A319 Passenger
  Operated by Avianca
Medellin CO
MDE17:19
6h 18m
1 Stop
Guayaquil EC
GYE23:37
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9343
  Medellin. CO
  MDE 17:19
  0h 56m
  145 Miles
  Bogota. CO
  BOG 18:15
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8391
  Bogota. CO
  BOG 21:32
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 23:37
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE10:49
6h 26m
1 Stop
Guayaquil EC
GYE17:15
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9213
  Medellin. CO
  MDE 10:49
  0h 50m
  145 Miles
  Bogota. CO
  BOG 11:39
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8383
  Bogota. CO
  BOG 15:10
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 17:15
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE07:16
6h 44m
1 Stop
Guayaquil EC
GYE14:00
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 8427
  Medellin. CO
  MDE 07:16
  0h 57m
  145 Miles
  Bogota. CO
  BOG 08:13
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8389
  Bogota. CO
  BOG 12:05
  1h 55m
  621 Miles
  Guayaquil. EC
  GYE 14:00
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE16:43
6h 54m
1 Stop
Guayaquil EC
GYE23:37
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9313
  Medellin. CO
  MDE 16:43
  0h 58m
  145 Miles
  Bogota. CO
  BOG 17:41
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8391
  Bogota. CO
  BOG 21:32
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 23:37
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE06:39
7h 9m
1 Stop
Guayaquil EC
GYE13:48
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 209
  Medellin. CO
  MDE 06:39
  1h 30m
  327 Miles
  Panama City. PA
  PTY 08:09
  Boeing 737-700 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 258
  Panama City. PA
  PTY 11:31
  2h 17m
  780 Miles
  Guayaquil. EC
  GYE 13:48
  Boeing 737-800 Passenger
  Operated by Copa Airlines

Flights from Medellin (MDE) to Guayaquil (GYE) with Star Alliance

Weather in Guayaquil

Flight schedules from Medellin to Guayaquil with Star Alliance member carriers

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

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Medellin - Guayaquil

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Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil