Flights from Medellin (MDE) to Guayaquil (GYE) with Star Alliance

Start your journey with just one click

Airline

1/15

Medellin

toGuayaquil

MDE-GYE

March 27, 2025

March 31, 2025

Sold byCopa Airlines

From

1,062,414COP Price subject to changes

Viewed:5 hours ago

Roundtrip

Economy

2/15

Medellin

toGuayaquil

MDE-GYE

February 12, 2025

March 10, 2025

Sold byAvianca

From

1,179,560COP Price subject to changes

Viewed:9 hours ago

Roundtrip

Economy

3/15

Medellin

toGuayaquil

MDE-GYE

March 27, 2025

March 31, 2025

Sold byCopa Airlines

From

248USD Price subject to changes

Viewed:5 hours ago

Roundtrip

Economy

4/15

Medellin

toGuayaquil

MDE-GYE

January 31, 2025

February 3, 2025

Sold byAvianca

From

1,190,310COP Price subject to changes

Viewed:2 minutes ago

Roundtrip

Economy

*Prices have been offered for round trips within the last 48 hours and might not be currently available. Not all Star Alliance Member Airlines or all fares/options are shown. Additional baggage fees, payment fees and fees for other optional services may apply. When booking, please check for restrictions on refunds, rebooking and baggage allowance that may apply. Prices may vary depending on the route and flights selected. Routings may include stopovers. Terms and conditions apply.

Weather in Guayaquil

Friday

moderate rain

17/01/2025

28°C

17/01/2025

moderate rain

Saturday

light rain

18/01/2025

30°C

18/01/2025

light rain

Sunday

light rain

19/01/2025

31°C

19/01/2025

light rain

Monday

moderate rain

20/01/2025

31°C

20/01/2025

moderate rain

Tuesday

moderate rain

21/01/2025

30°C

21/01/2025

moderate rain

Wednesday

light rain

22/01/2025

30°C

22/01/2025

light rain

Thursday

light rain

23/01/2025

30°C

23/01/2025

light rain

Flight schedules from Medellin to Guayaquil with Star Alliance member carriers

Please note that the flight schedules of our member carriers are subject to change on short notice. We recommend using our member airlines information page. for the latest flight updates, details on booking flexibility, as well as specific Frequent Flyer Program information.

Outbound (28)

Sort by

Medellin CO
MDE16:55
1h 50m
No stops
Guayaquil EC
GYE18:45
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 8399
  Medellin. CO
  MDE 16:55
  1h 50m
  653 Miles
  Guayaquil. EC
  GYE 18:45
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE04:56
4h 4m
1 Stop
Guayaquil EC
GYE09:00
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 8475
  Medellin. CO
  MDE 04:56
  0h 58m
  145 Miles
  Bogota. CO
  BOG 05:54
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8385
  Bogota. CO
  BOG 07:10
  1h 50m
  621 Miles
  Guayaquil. EC
  GYE 09:00
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE18:29
4h 11m
1 Stop
Guayaquil EC
GYE22:40
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9375
  Medellin. CO
  MDE 18:29
  0h 55m
  145 Miles
  Bogota. CO
  BOG 19:24
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8371
  Bogota. CO
  BOG 20:40
  2h 0m
  621 Miles
  Guayaquil. EC
  GYE 22:40
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE13:03
4h 12m
1 Stop
Guayaquil EC
GYE17:15
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9329
  Medellin. CO
  MDE 13:03
  0h 56m
  145 Miles
  Bogota. CO
  BOG 13:59
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8383
  Bogota. CO
  BOG 15:10
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 17:15
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE19:15
4h 22m
1 Stop
Guayaquil EC
GYE23:37
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9553
  Medellin. CO
  MDE 19:15
  0h 57m
  145 Miles
  Bogota. CO
  BOG 20:12
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8391
  Bogota. CO
  BOG 21:32
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 23:37
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE04:35
4h 25m
1 Stop
Guayaquil EC
GYE09:00
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9653
  Medellin. CO
  MDE 04:35
  0h 58m
  145 Miles
  Bogota. CO
  BOG 05:33
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8385
  Bogota. CO
  BOG 07:10
  1h 50m
  621 Miles
  Guayaquil. EC
  GYE 09:00
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE09:23
4h 26m
1 Stop
Guayaquil EC
GYE13:49
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 398
  Medellin. CO
  MDE 09:23
  1h 28m
  327 Miles
  Panama City. PA
  PTY 10:51
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 258
  Panama City. PA
  PTY 11:31
  2h 18m
  780 Miles
  Guayaquil. EC
  GYE 13:49
  Boeing 737-800 Passenger
  Operated by Copa Airlines
Medellin CO
MDE19:03
4h 34m
1 Stop
Guayaquil EC
GYE23:37
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 8415
  Medellin. CO
  MDE 19:03
  0h 56m
  145 Miles
  Bogota. CO
  BOG 19:59
  Airbus A319 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8391
  Bogota. CO
  BOG 21:32
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 23:37
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE06:41
4h 38m
1 Stop
Guayaquil EC
GYE11:19
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 209
  Medellin. CO
  MDE 06:41
  1h 28m
  327 Miles
  Panama City. PA
  PTY 08:09
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 273
  Panama City. PA
  PTY 09:01
  2h 18m
  780 Miles
  Guayaquil. EC
  GYE 11:19
  Boeing 737 MAX 9 Passenger / BBJ MAX 9
  Operated by Copa Airlines
Medellin CO
MDE05:06
4h 44m
1 Stop
Guayaquil EC
GYE09:50
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9725
  Medellin. CO
  MDE 05:06
  1h 3m
  145 Miles
  Bogota. CO
  BOG 06:09
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 77
  Bogota. CO
  BOG 08:00
  1h 50m
  621 Miles
  Guayaquil. EC
  GYE 09:50
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE04:56
4h 54m
1 Stop
Guayaquil EC
GYE09:50
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 8475
  Medellin. CO
  MDE 04:56
  0h 58m
  145 Miles
  Bogota. CO
  BOG 05:54
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 77
  Bogota. CO
  BOG 08:00
  1h 50m
  621 Miles
  Guayaquil. EC
  GYE 09:50
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE18:29
5h 8m
1 Stop
Guayaquil EC
GYE23:37
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9375
  Medellin. CO
  MDE 18:29
  0h 55m
  145 Miles
  Bogota. CO
  BOG 19:24
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8391
  Bogota. CO
  BOG 21:32
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 23:37
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE15:34
5h 11m
1 Stop
Guayaquil EC
GYE20:45
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 154
  Medellin. CO
  MDE 15:34
  1h 28m
  327 Miles
  Panama City. PA
  PTY 17:02
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 213
  Panama City. PA
  PTY 18:25
  2h 20m
  780 Miles
  Guayaquil. EC
  GYE 20:45
  Boeing 737 MAX 9 Passenger / BBJ MAX 9
  Operated by Copa Airlines
Medellin CO
MDE04:35
5h 15m
1 Stop
Guayaquil EC
GYE09:50
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9653
  Medellin. CO
  MDE 04:35
  0h 58m
  145 Miles
  Bogota. CO
  BOG 05:33
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 77
  Bogota. CO
  BOG 08:00
  1h 50m
  621 Miles
  Guayaquil. EC
  GYE 09:50
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE18:23
5h 20m
1 Stop
Guayaquil EC
GYE23:43
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 157
  Medellin. CO
  MDE 18:23
  1h 25m
  327 Miles
  Panama City. PA
  PTY 19:48
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 301
  Panama City. PA
  PTY 21:25
  2h 18m
  780 Miles
  Guayaquil. EC
  GYE 23:43
  Boeing 737-800 Passenger
  Operated by Copa Airlines
Medellin CO
MDE17:19
5h 21m
1 Stop
Guayaquil EC
GYE22:40
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9343
  Medellin. CO
  MDE 17:19
  0h 56m
  145 Miles
  Bogota. CO
  BOG 18:15
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8371
  Bogota. CO
  BOG 20:40
  2h 0m
  621 Miles
  Guayaquil. EC
  GYE 22:40
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE11:52
5h 23m
1 Stop
Guayaquil EC
GYE17:15
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9339
  Medellin. CO
  MDE 11:52
  0h 56m
  145 Miles
  Bogota. CO
  BOG 12:48
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8383
  Bogota. CO
  BOG 15:10
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 17:15
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE11:59
5h 37m
1 Stop
Guayaquil EC
GYE17:36
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 506
  Medellin. CO
  MDE 11:59
  1h 28m
  327 Miles
  Panama City. PA
  PTY 13:27
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 378
  Panama City. PA
  PTY 15:19
  2h 17m
  780 Miles
  Guayaquil. EC
  GYE 17:36
  Boeing 737-800 Passenger
  Operated by Copa Airlines
Medellin CO
MDE16:43
5h 57m
1 Stop
Guayaquil EC
GYE22:40
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9313
  Medellin. CO
  MDE 16:43
  0h 58m
  145 Miles
  Bogota. CO
  BOG 17:41
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8371
  Bogota. CO
  BOG 20:40
  2h 0m
  621 Miles
  Guayaquil. EC
  GYE 22:40
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE11:30
6h 6m
1 Stop
Guayaquil EC
GYE17:36
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 856
  Medellin. CO
  MDE 11:30
  1h 28m
  327 Miles
  Panama City. PA
  PTY 12:58
  Boeing 737-700 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 378
  Panama City. PA
  PTY 15:19
  2h 17m
  780 Miles
  Guayaquil. EC
  GYE 17:36
  Boeing 737-800 Passenger
  Operated by Copa Airlines
Medellin CO
MDE11:07
6h 8m
1 Stop
Guayaquil EC
GYE17:15
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9349
  Medellin. CO
  MDE 11:07
  0h 52m
  145 Miles
  Bogota. CO
  BOG 11:59
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8383
  Bogota. CO
  BOG 15:10
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 17:15
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE05:11
6h 8m
1 Stop
Guayaquil EC
GYE11:19
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 151
  Medellin. CO
  MDE 05:11
  1h 23m
  327 Miles
  Panama City. PA
  PTY 06:34
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 273
  Panama City. PA
  PTY 09:01
  2h 18m
  780 Miles
  Guayaquil. EC
  GYE 11:19
  Boeing 737 MAX 9 Passenger / BBJ MAX 9
  Operated by Copa Airlines
Medellin CO
MDE16:31
6h 9m
1 Stop
Guayaquil EC
GYE22:40
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 8405
  Medellin. CO
  MDE 16:31
  0h 58m
  145 Miles
  Bogota. CO
  BOG 17:29
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8371
  Bogota. CO
  BOG 20:40
  2h 0m
  621 Miles
  Guayaquil. EC
  GYE 22:40
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE17:19
6h 18m
1 Stop
Guayaquil EC
GYE23:37
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9343
  Medellin. CO
  MDE 17:19
  0h 56m
  145 Miles
  Bogota. CO
  BOG 18:15
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8391
  Bogota. CO
  BOG 21:32
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 23:37
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE16:43
6h 54m
1 Stop
Guayaquil EC
GYE23:37
Medellin - Guayaquil
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9313
  Medellin. CO
  MDE 16:43
  0h 58m
  145 Miles
  Bogota. CO
  BOG 17:41
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 8391
  Bogota. CO
  BOG 21:32
  2h 5m
  621 Miles
  Guayaquil. EC
  GYE 23:37
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE06:41
7h 8m
1 Stop
Guayaquil EC
GYE13:49
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 209
  Medellin. CO
  MDE 06:41
  1h 28m
  327 Miles
  Panama City. PA
  PTY 08:09
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 258
  Panama City. PA
  PTY 11:31
  2h 18m
  780 Miles
  Guayaquil. EC
  GYE 13:49
  Boeing 737-800 Passenger
  Operated by Copa Airlines
Medellin CO
MDE10:00
7h 36m
1 Stop
Guayaquil EC
GYE17:36
Medellin - Guayaquil
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 834
  Medellin. CO
  MDE 10:00
  1h 28m
  327 Miles
  Panama City. PA
  PTY 11:28
  Boeing 737 MAX 9 Passenger / BBJ MAX 9
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 378
  Panama City. PA
  PTY 15:19
  2h 17m
  780 Miles
  Guayaquil. EC
  GYE 17:36
  Boeing 737-800 Passenger
  Operated by Copa Airlines
Medellin CO
MDE06:41
10h 34m
2 Stops
Guayaquil EC
GYE17:15
Medellin - Guayaquil
Star Alliance
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 209
  Medellin. CO
  MDE 06:41
  1h 28m
  327 Miles
  Panama City. PA
  PTY 08:09
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Avianca AV 8383
  Panama City. PA
  PTY 11:25
  3h 40m
  780 Miles
  Guayaquil. EC
  GYE 17:15
  Airbus A320 Passenger
  Operated by Avianca

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Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil

Medellin - Guayaquil