Flights from Medellin (MDE) to Santiago (SCL) with Star Alliance

Start your journey with just one click

Airline

1/30

Medellin

toSantiago

MDE-SCL

April 2, 2025

April 9, 2025

Sold byAvianca

From

1,650,740COP Price subject to changes

Viewed:7 hours ago

Roundtrip

Economy

2/30

Medellin

toSantiago

MDE-SCL

April 2, 2025

April 12, 2025

Sold byCopa Airlines

From

1,707,095COP Price subject to changes

Viewed:9 hours ago

Roundtrip

Economy

3/30

Medellin

toSantiago

MDE-SCL

March 12, 2025

March 18, 2025

Sold byAvianca

From

1,809,780COP Price subject to changes

Viewed:an hour ago

Roundtrip

Economy

4/30

Medellin

toSantiago

MDE-SCL

March 6, 2025

March 13, 2025

Sold byCopa Airlines

From

1,803,494COP Price subject to changes

Viewed:4 hours ago

Roundtrip

Economy

*Prices have been offered for round trips within the last 48 hours and might not be currently available. Not all Star Alliance Member Airlines or all fares/options are shown. Additional baggage fees, payment fees and fees for other optional services may apply. When booking, please check for restrictions on refunds, rebooking and baggage allowance that may apply. Prices may vary depending on the route and flights selected. Routings may include stopovers. Terms and conditions apply.

Weather in Santiago

Saturday

sky is clear

18/01/2025

27°C

18/01/2025

sky is clear

Sunday

sky is clear

19/01/2025

30°C

19/01/2025

sky is clear

Monday

sky is clear

20/01/2025

30°C

20/01/2025

sky is clear

Tuesday

sky is clear

21/01/2025

26°C

21/01/2025

sky is clear

Wednesday

sky is clear

22/01/2025

26°C

22/01/2025

sky is clear

Thursday

sky is clear

23/01/2025

27°C

23/01/2025

sky is clear

Friday

sky is clear

24/01/2025

27°C

24/01/2025

sky is clear

Flight schedules from Medellin to Santiago with Star Alliance member carriers

Please note that the flight schedules of our member carriers are subject to change on short notice. We recommend using our member airlines information page. for the latest flight updates, details on booking flexibility, as well as specific Frequent Flyer Program information.

Outbound (18)

Sort by

Medellin CO
MDE19:03
8h 7m
1 Stop
Santiago CL
SCL05:10
+1 day/s
Medellin - Santiago
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 8415
  Medellin. CO
  MDE 19:03
  0h 56m
  145 Miles
  Bogota. CO
  BOG 19:59
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 97
  Bogota. CO
  BOG 21:30
  5h 40m
  2656 Miles
  Santiago. CL
  SCL 05:10
  Boeing 787-8
  Operated by Avianca
Medellin CO
MDE13:03
8h 37m
1 Stop
Santiago CL
SCL23:40
Medellin - Santiago
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9329
  Medellin. CO
  MDE 13:03
  0h 56m
  145 Miles
  Bogota. CO
  BOG 13:59
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 241
  Bogota. CO
  BOG 15:30
  6h 10m
  2656 Miles
  Santiago. CL
  SCL 23:40
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE18:29
8h 41m
1 Stop
Santiago CL
SCL05:10
+1 day/s
Medellin - Santiago
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9375
  Medellin. CO
  MDE 18:29
  0h 55m
  145 Miles
  Bogota. CO
  BOG 19:24
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 97
  Bogota. CO
  BOG 21:30
  5h 40m
  2656 Miles
  Santiago. CL
  SCL 05:10
  Boeing 787-8
  Operated by Avianca
Medellin CO
MDE09:23
8h 56m
1 Stop
Santiago CL
SCL20:19
Medellin - Santiago
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 398
  Medellin. CO
  MDE 09:23
  1h 28m
  327 Miles
  Panama City. PA
  PTY 10:51
  Boeing 737 MAX 9 Passenger / BBJ MAX 9
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 395
  Panama City. PA
  PTY 11:47
  6h 32m
  3004 Miles
  Santiago. CL
  SCL 20:19
  Boeing 737 MAX 9 Passenger / BBJ MAX 9
  Operated by Copa Airlines
Medellin CO
MDE12:26
9h 14m
1 Stop
Santiago CL
SCL23:40
Medellin - Santiago
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9346
  Medellin. CO
  MDE 12:26
  0h 56m
  145 Miles
  Bogota. CO
  BOG 13:22
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 241
  Bogota. CO
  BOG 15:30
  6h 10m
  2656 Miles
  Santiago. CL
  SCL 23:40
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE18:23
9h 37m
1 Stop
Santiago CL
SCL06:00
+1 day/s
Medellin - Santiago
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 157
  Medellin. CO
  MDE 18:23
  1h 25m
  327 Miles
  Panama City. PA
  PTY 19:48
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 277
  Panama City. PA
  PTY 21:28
  6h 32m
  3004 Miles
  Santiago. CL
  SCL 06:00
  Boeing 737 MAX 9 Passenger / BBJ MAX 9
  Operated by Copa Airlines
Medellin CO
MDE11:52
9h 48m
1 Stop
Santiago CL
SCL23:40
Medellin - Santiago
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9339
  Medellin. CO
  MDE 11:52
  0h 56m
  145 Miles
  Bogota. CO
  BOG 12:48
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 241
  Bogota. CO
  BOG 15:30
  6h 10m
  2656 Miles
  Santiago. CL
  SCL 23:40
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE17:19
9h 51m
1 Stop
Santiago CL
SCL05:10
+1 day/s
Medellin - Santiago
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9343
  Medellin. CO
  MDE 17:19
  0h 56m
  145 Miles
  Bogota. CO
  BOG 18:15
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 97
  Bogota. CO
  BOG 21:30
  5h 40m
  2656 Miles
  Santiago. CL
  SCL 05:10
  Boeing 787-8
  Operated by Avianca
Medellin CO
MDE15:34
9h 51m
1 Stop
Santiago CL
SCL03:25
+1 day/s
Medellin - Santiago
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 154
  Medellin. CO
  MDE 15:34
  1h 28m
  327 Miles
  Panama City. PA
  PTY 17:02
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 172
  Panama City. PA
  PTY 18:51
  6h 34m
  3004 Miles
  Santiago. CL
  SCL 03:25
  Boeing 737-800 Passenger
  Operated by Copa Airlines
Medellin CO
MDE11:59
9h 56m
1 Stop
Santiago CL
SCL23:55
Medellin - Santiago
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 506
  Medellin. CO
  MDE 11:59
  1h 28m
  327 Miles
  Panama City. PA
  PTY 13:27
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 497
  Panama City. PA
  PTY 15:14
  6h 41m
  3004 Miles
  Santiago. CL
  SCL 23:55
  Boeing 737-800 Passenger
  Operated by Copa Airlines
Medellin CO
MDE15:34
10h 5m
1 Stop
Santiago CL
SCL03:39
+1 day/s
Medellin - Santiago
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 154
  Medellin. CO
  MDE 15:34
  1h 28m
  327 Miles
  Panama City. PA
  PTY 17:02
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 474
  Panama City. PA
  PTY 19:05
  6h 34m
  3004 Miles
  Santiago. CL
  SCL 03:39
  Boeing 737-800 Passenger
  Operated by Copa Airlines
Medellin CO
MDE11:59
10h 14m
1 Stop
Santiago CL
SCL00:13
+1 day/s
Medellin - Santiago
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 506
  Medellin. CO
  MDE 11:59
  1h 28m
  327 Miles
  Panama City. PA
  PTY 13:27
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 171
  Panama City. PA
  PTY 15:32
  6h 41m
  3004 Miles
  Santiago. CL
  SCL 00:13
  Boeing 737-800 Passenger
  Operated by Copa Airlines
Medellin CO
MDE11:30
10h 25m
1 Stop
Santiago CL
SCL23:55
Medellin - Santiago
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 856
  Medellin. CO
  MDE 11:30
  1h 28m
  327 Miles
  Panama City. PA
  PTY 12:58
  Boeing 737-700 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 497
  Panama City. PA
  PTY 15:14
  6h 41m
  3004 Miles
  Santiago. CL
  SCL 23:55
  Boeing 737-800 Passenger
  Operated by Copa Airlines
Medellin CO
MDE16:43
10h 27m
1 Stop
Santiago CL
SCL05:10
+1 day/s
Medellin - Santiago
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9313
  Medellin. CO
  MDE 16:43
  0h 58m
  145 Miles
  Bogota. CO
  BOG 17:41
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 97
  Bogota. CO
  BOG 21:30
  5h 40m
  2656 Miles
  Santiago. CL
  SCL 05:10
  Boeing 787-8
  Operated by Avianca
Medellin CO
MDE11:07
10h 33m
1 Stop
Santiago CL
SCL23:40
Medellin - Santiago
Avianca
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Avianca AV 9349
  Medellin. CO
  MDE 11:07
  0h 52m
  145 Miles
  Bogota. CO
  BOG 11:59
  Airbus A320 Passenger
  Operated by Avianca
2. Flight 2Avianca AV 241
  Bogota. CO
  BOG 15:30
  6h 10m
  2656 Miles
  Santiago. CL
  SCL 23:40
  Airbus A320 Passenger
  Operated by Avianca
Medellin CO
MDE11:30
10h 43m
1 Stop
Santiago CL
SCL00:13
+1 day/s
Medellin - Santiago
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 856
  Medellin. CO
  MDE 11:30
  1h 28m
  327 Miles
  Panama City. PA
  PTY 12:58
  Boeing 737-700 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 171
  Panama City. PA
  PTY 15:32
  6h 41m
  3004 Miles
  Santiago. CL
  SCL 00:13
  Boeing 737-800 Passenger
  Operated by Copa Airlines
Medellin CO
MDE06:41
11h 38m
1 Stop
Santiago CL
SCL20:19
Medellin - Santiago
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 209
  Medellin. CO
  MDE 06:41
  1h 28m
  327 Miles
  Panama City. PA
  PTY 08:09
  Boeing 737-700 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 395
  Panama City. PA
  PTY 11:47
  6h 32m
  3004 Miles
  Santiago. CL
  SCL 20:19
  Boeing 737 MAX 9 Passenger / BBJ MAX 9
  Operated by Copa Airlines
Medellin CO
MDE10:00
11h 55m
1 Stop
Santiago CL
SCL23:55
Medellin - Santiago
Copa Airlines
Flight Operates
1. Mon
2. Tue
3. Wed
4. Thu
5. Fri
6. Sat
7. Sun
1. Flight 1Copa Airlines CM 834
  Medellin. CO
  MDE 10:00
  1h 28m
  327 Miles
  Panama City. PA
  PTY 11:28
  Boeing 737-800 Passenger
  Operated by Copa Airlines
2. Flight 2Copa Airlines CM 497
  Panama City. PA
  PTY 15:14
  6h 41m
  3004 Miles
  Santiago. CL
  SCL 23:55
  Boeing 737-800 Passenger
  Operated by Copa Airlines

Start your journey with just one click

Medellin - Santiago

Medellin - Santiago

Medellin - Santiago

Medellin - Santiago

Medellin - Santiago

Medellin - Santiago

Medellin - Santiago

Medellin - Santiago

Medellin - Santiago

Medellin - Santiago

Medellin - Santiago

Medellin - Santiago

Medellin - Santiago

Medellin - Santiago

Medellin - Santiago

Medellin - Santiago

Medellin - Santiago

Medellin - Santiago